Beta-lactam-antibiotics (beta-lactam antibiotics) are antibiotics that have a beta-lactam ring in their molecular structure. These include penicillin derivatives (penicillins), cephalosporins (monophytes), carbapenems, and carbaphymes, which inhibit cell wall biosynthesis in most bacterial β-lactam bacteria. By 2003, when measured by sales, more than half of all commercially available antibiotics in use were β-lactam compounds. The discovered β-lactam antibiotic, penicillin, was isolated from Penicillium notatum (hence the name Penicillium chrysogenum).
Bacteria often develop resistance to β-lactam antibiotics.-lactam, an enzyme that attacks the β-lactam ring. To overcome this resistance, cla-lactam antibiotics can be given along with β-lactamase inhibitors such as clavulanic acid.
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