Ofloxacin is a quinolone antibiotic that is useful in treating many bacterial infections. When injected into a vein by mouth or injection, these include pneumonia, cellulitis, urinary tract infections, prostatitis, plague, and some types of infectious diarrhea. In addition to drugs used to treat multidrug-resistant tuberculosis, use more. Eye drops can be used for superficial bacterial infections of the eye and ear drops can be used for otitis media when there is a hole in the ear.
When taken by mouth, common side effects include vomiting, diarrhea, headaches, and rashes. Other serious side effects include mild rupture, numbness due to nerve damage, seizures, and psychosis. Not generally recommended for use during pregnancy. Ofloxacin is in the fluoroquinolone family of drugs. It works by interfering with the DNA of bacteria. Ofloxacin was patented in 1980 and approved for medical use in 1985. It is on the World Health Organization’s list of essential medicines. Ofloxacin is available as a generic drug. In 2017, it was the 278th most prescribed drug in the United States, with over 1 million prescriptions.
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